villus sampling
A prenatal diagnostic procedure that obtains chorionic villus tissue for genetic analysis, typically performed between 10-13 weeks of pregnancy.
Full Definition
Villus sampling, more precisely known as chorionic villus sampling (CVS), is an invasive prenatal diagnostic test that involves obtaining a small sample of placental tissue (chorionic villi) for genetic analysis. The procedure can be performed either transcervically (through the cervix) or transabdominally (through the maternal abdomen), depending on placental position. It provides earlier diagnosis than amniocentesis but carries a small risk of miscarriage and potential for maternal cell contamination or confined placental mosaicism.
Usage
Usage note: The full term 'chorionic villus sampling' is preferred in formal documentation.
In Context
- "Villus sampling confirmed the presence of the familial genetic mutation at 11 weeks gestation." — Prenatal diagnosis report
- "The couple opted for villus sampling rather than amniocentesis to obtain earlier diagnostic information." — Patient consultation note