sleep-related hypoventilation
Decreased ventilation during sleep resulting in elevated carbon dioxide levels and reduced oxygen saturation.
Full Definition
Sleep-related hypoventilation is a sleep-disordered breathing condition characterized by sustained periods of inadequate ventilation during sleep, leading to hypercapnia and hypoxemia. Unlike obstructive sleep apnea, this condition involves reduced respiratory drive or impaired respiratory mechanics rather than upper airway obstruction. It commonly occurs in patients with neuromuscular disorders, chest wall deformities, or severe obesity. Diagnosis requires demonstration of elevated CO2 levels during sleep, often measured through transcutaneous or end-tidal monitoring during polysomnography.
Usage
Usage note: Distinguish from 'obesity hypoventilation syndrome' which has specific BMI criteria.
In Context
- "The patient with muscular dystrophy developed sleep-related hypoventilation requiring nocturnal ventilatory support." — Neurology consultation
- "Transcutaneous CO2 monitoring revealed significant sleep-related hypoventilation with levels exceeding 50 mmHg." — Sleep study interpretation