Intermediate
Technical
IVT
SIRS
Also written as: SIRS — Systemic Inflammatory Response Syndrome
Systemic Inflammatory Response Syndrome, a clinical response to infection or other inflammatory insults.
Full Definition
SIRS represents the body's inflammatory response to various clinical insults including infection, burns, trauma, or pancreatitis. Diagnosed when two or more criteria are met: temperature >38°C or <36°C, heart rate >90 bpm, respiratory rate >20 breaths/min or PaCO2 <32 mmHg, and white blood cell count >12,000 or <4,000 cells/mm³. In surgical critical care, SIRS often precedes sepsis and serves as an early warning system for deteriorating patients.
Usage
Usage note: SIRS is a broader category that includes but is not limited to sepsis.
In Context
- "The patient developed SIRS following the complicated bowel resection." — Progress note
- "Early recognition of SIRS criteria prompted immediate antibiotic therapy." — Quality improvement report
Also known as
Systemic Inflammatory Response Syndrome
Don't confuse with
sepsis
septic shock