Advanced
Technical
IVT
biomarker-directed therapy
Cancer treatment approach that uses specific molecular markers to guide therapeutic decisions and drug selection.
Full Definition
Biomarker-directed therapy represents precision medicine in oncology, where treatment decisions are based on specific molecular characteristics of a patient's tumor rather than solely on histological appearance or anatomical location. This approach involves testing tumor tissue for genetic mutations, protein expression, or other biological markers that predict response to particular therapies. Biomarker-directed therapy has revolutionized cancer treatment by enabling more personalized and effective therapeutic strategies while potentially reducing unnecessary toxicity from ineffective treatments.
In Context
- "The tumor's molecular profile supports biomarker-directed therapy with a CDK4/6 inhibitor." — Pathology report
- "Biomarker-directed therapy has improved outcomes in metastatic colorectal cancer." — Clinical study manuscript
Also known as
precision oncology
personalized medicine
molecular-guided therapy
Contrasted with
empirical therapy
Don't confuse with
targeted therapy
biomarker testing