circumferential resection margin
The radial margin around a tumor specimen, particularly important in rectal cancer surgery for assessing complete tumor removal.
Full Definition
The circumferential resection margin (CRM) represents the shortest distance between the tumor edge and the resection margin in specimens removed during surgery, especially crucial in colorectal and other gastrointestinal cancers. A positive CRM (typically defined as ≤1mm) indicates potential incomplete tumor removal and higher risk of local recurrence. Pathologists measure this margin carefully as it directly impacts staging, prognosis, and treatment planning decisions.
Usage
Usage note: Always specify the measurement distance when describing CRM status.
In Context
- "The pathology report indicated a negative circumferential resection margin of 3mm." — surgical pathology report
- "The surgeon emphasized the importance of achieving an adequate circumferential resection margin during the anterior resection." — operative note