locoregional control
Successful prevention or management of cancer recurrence in the primary tumor site and nearby lymph nodes.
Full Definition
Locoregional control refers to the absence of cancer recurrence in the primary tumor bed and regional lymph node basins following treatment. This oncological endpoint is distinct from distant metastatic control and is primarily achieved through adequate surgical resection, radiation therapy, or combined modality treatment. Locoregional control is a critical measure of treatment success in surgical oncology and strongly correlates with overall survival in many cancer types. Assessment of locoregional control requires long-term follow-up with clinical examination and appropriate imaging studies.
In Context
- "The five-year locoregional control rate was 92% following complete resection." — Clinical study results
- "Radiation therapy was added to improve locoregional control in high-risk patients." — Treatment recommendation