molecular tumor profiling

Full Definition

Molecular tumor profiling involves sophisticated laboratory techniques to analyze the genetic makeup and molecular characteristics of cancer cells. This process includes DNA sequencing, RNA expression analysis, and protein marker assessment to identify specific mutations, amplifications, or other alterations that may influence treatment response. The results of molecular tumor profiling are increasingly used to select targeted therapies, predict prognosis, and determine eligibility for clinical trials. This approach has become standard practice in many cancer types and is fundamental to personalized cancer care.

In Context

• "Molecular tumor profiling revealed a BRAF mutation amenable to targeted therapy." — Pathology report
• "The molecular tumor profiling results will be discussed at next week's tumor board." — Clinical documentation