bronchial brushings
Cytological specimens obtained by brushing the bronchial wall during bronchoscopy for cancer diagnosis.
Full Definition
Bronchial brushings are cytological samples collected using a small brush passed through the working channel of a bronchoscope to sample the bronchial wall or visible lesions. This technique is commonly used in the evaluation of suspected lung cancer, particularly for central lesions visible during bronchoscopy. The brush collects epithelial cells and other material that can be examined microscopically for malignant cells. Bronchial brushings have higher diagnostic yield than bronchial washings alone and are often performed in conjunction with endobronchial biopsy and bronchoalveolar lavage as part of a comprehensive bronchoscopic evaluation. The specimens are typically processed for conventional cytology and may also be used for molecular testing when adequate tumor cells are present.
Usage
Usage note: Plural form is standard; distinguish from other bronchoscopic sampling methods.
In Context
- "Bronchial brushings from the right main bronchus revealed malignant cells consistent with squamous cell carcinoma." — Pathology report
- "The diagnostic yield was improved by combining endobronchial biopsy with bronchial brushings." — Procedure note