endobronchial lesion
An abnormal growth or mass within the bronchial lumen, often representing primary lung cancer or metastatic disease.
Full Definition
An endobronchial lesion is an abnormal tissue growth located within the lumen of the bronchial tree, visible during bronchoscopy as a polypoid mass, mucosal irregularity, or luminal narrowing. In thoracic oncology, endobronchial lesions commonly represent primary lung cancers, particularly squamous cell carcinomas and small cell lung cancers, which have a propensity for central, endobronchial growth. These lesions may cause bronchial obstruction leading to post-obstructive pneumonia, atelectasis, or hemoptysis. Endobronchial lesions are typically amenable to direct bronchoscopic biopsy, brushings, and washings, providing high diagnostic yield. Treatment may involve endobronchial therapies such as laser resection, electrocautery, or stent placement for palliation of obstruction.
Usage
Usage note: Distinguish from peribronchial or extrabronchial lesions affecting the airways.
In Context
- "Bronchoscopy revealed a polypoid endobronchial lesion completely obstructing the right upper lobe bronchus." — Procedure note
- "The endobronchial lesion was successfully treated with laser ablation to relieve airway obstruction." — Treatment report