NSCLC
Also written as: NSCLC — non-small cell lung cancer
Non-small cell lung cancer, the most common type of lung cancer encompassing adenocarcinoma, squamous cell, and large cell carcinomas.
Full Definition
Non-small cell lung cancer (NSCLC) is a broad category representing approximately 85% of all lung cancers, distinguished from small cell lung cancer by different biological behavior, treatment approaches, and prognosis. NSCLC includes three main histological subtypes: adenocarcinoma (most common), squamous cell carcinoma, and large cell carcinoma. The distinction is crucial because NSCLC generally has a better prognosis than small cell lung cancer and is more amenable to surgical resection in early stages. Treatment strategies for NSCLC have evolved significantly with the introduction of targeted therapies and immunotherapy based on molecular profiling.
Usage
Usage note: Always use capital letters; spell out on first use in formal documents.
In Context
- "The patient was diagnosed with stage IIIA NSCLC and referred for multimodal therapy." — Oncology consultation
- "Molecular testing is standard practice for advanced NSCLC to guide targeted therapy." — Treatment protocol