pathological staging
Cancer staging based on histopathological examination of resected tumor specimens and lymph nodes.
Full Definition
Pathological staging (pTNM) represents the definitive staging of cancer based on histopathological examination of surgically resected specimens, including the primary tumor, regional lymph nodes, and any other tissues removed during surgery. In thoracic oncology, pathological staging provides more accurate prognostic information than clinical staging, as it allows direct assessment of tumor size, invasion depth, nodal involvement, and surgical margins. Pathological staging may differ from clinical staging due to limitations of preoperative imaging in detecting microscopic disease or accurately measuring tumor dimensions. The pathological stage guides adjuvant therapy decisions and provides crucial prognostic information for patient counseling and follow-up planning.
Usage
Usage note: Distinguish from clinical staging; use 'p' prefix for pathological staging (e.g., pT2a vs. cT2a).
In Context
- "Pathological staging revealed pT2aN1M0 disease with three positive hilar lymph nodes." — Pathology report
- "The pathological staging was more advanced than clinical staging due to occult nodal metastases." — Multidisciplinary conference note