PSA
Pronunciation: PEE-ess-ay
Also written as: PSA — Prostate-Specific Antigen
Blood test measuring prostate-specific antigen levels for prostate cancer screening.
Full Definition
Prostate-specific antigen (PSA) is a glycoprotein produced by prostate epithelial cells, measured via serum blood test for prostate cancer screening and monitoring. Elevated PSA levels may indicate prostate cancer, benign prostatic hyperplasia, prostatitis, or other prostate conditions. PSA values are interpreted considering patient age, digital rectal examination findings, and trends over time. Normal ranges vary by age, with generally accepted upper limits of 4.0 ng/mL, though this threshold remains controversial.
Usage
Usage note: Always capitalize; distinguish from related terms like free PSA ratio and PSA density.
In Context
- "The patient's PSA level increased from 2.1 to 6.8 ng/mL over two years, prompting referral for biopsy." — Laboratory report
- "Post-prostatectomy PSA remains undetectable at six months follow-up." — Oncology follow-up note