drug-eluting stent
Also written as: DES — Drug-Eluting Stent
A expandable metal mesh tube coated with medication that prevents restenosis when implanted in blood vessels.
Full Definition
A drug-eluting stent (DES) is a coronary or peripheral stent that releases antiproliferative drugs over time to reduce the risk of in-stent restenosis. The stent platform is coated with a polymer that controls the release of drugs such as sirolimus, everolimus, or paclitaxel. DES technology has significantly improved long-term patency rates compared to bare metal stents by inhibiting smooth muscle cell proliferation and neointimal hyperplasia. Modern DES designs focus on biocompatible polymers and optimized drug release kinetics to minimize late stent thrombosis while maintaining efficacy against restenosis.
Usage
Usage note: Distinguish from drug-coated balloons, which deliver medication without permanent implantation.
In Context
- "The second-generation drug-eluting stent demonstrated superior safety and efficacy profiles in this patient population." — Research abstract
- "DES implantation was performed in the mid-LAD with optimal angiographic result." — Catheterization report