MACE
Pronunciation: MAYS
Also written as: MACE — major adverse cardiac events
Major adverse cardiac events; composite endpoint including death, myocardial infarction, and target vessel revascularization.
Full Definition
Major adverse cardiac events (MACE) is a composite clinical endpoint commonly used in cardiovascular research and clinical practice to evaluate treatment outcomes. MACE typically includes cardiac death, myocardial infarction, and target vessel revascularization, though definitions may vary between studies. This endpoint provides a comprehensive assessment of treatment safety and efficacy by capturing the most clinically relevant adverse outcomes following cardiovascular interventions.
Usage
Usage note: Define specific components when used in research contexts as definitions vary.
In Context
- "The primary endpoint of MACE at one year was significantly reduced in the drug-eluting stent group." — Clinical trial report
- "Patient follow-up revealed no MACE events during the six-month observation period." — Clinical documentation