MLD
Also written as: MLD — Minimum Lumen Diameter
Minimum lumen diameter, the narrowest point within a stenotic segment as measured by quantitative angiography.
Full Definition
MLD stands for minimum lumen diameter, a key quantitative angiographic parameter that represents the smallest cross-sectional diameter of the vessel lumen within a stenotic segment. This measurement is crucial for assessing stenosis severity, selecting appropriate device sizes, and evaluating procedural outcomes. MLD is typically measured in millimeters and serves as a primary endpoint in many clinical trials investigating interventional devices and techniques. The measurement is obtained using computer-assisted quantitative coronary angiography and provides more objective assessment than visual estimation. Changes in MLD from baseline to follow-up are used to calculate late lumen loss, an important measure of long-term vessel response to intervention.
Usage
Usage note: Always specify the measurement method (visual vs. QCA) when reporting MLD.
In Context
- "The pre-procedural MLD was 0.8 mm, increasing to 2.9 mm following stent implantation." — QCA analysis report
- "At six-month follow-up, the MLD remained stable at 2.5 mm with no evidence of restenosis." — Clinical trial follow-up