coagulopathy
Pronunciation: ko-AG-yoo-lop-ah-thee
Blood clotting disorder affecting hemostasis, either increasing bleeding risk or thrombotic tendency.
Full Definition
Coagulopathy refers to any abnormality in the blood coagulation system that disrupts normal hemostasis. These disorders can be inherited (such as hemophilia or Factor V Leiden) or acquired (such as liver disease, medication effects, or consumption during massive bleeding). In vascular medicine, coagulopathies are crucial considerations for surgical planning, anticoagulation management, and understanding thrombotic or hemorrhagic complications. Assessment typically involves coagulation studies including PT/INR, aPTT, and specialized factor assays.
Usage
Usage note: Distinguish between bleeding disorders and prothrombotic coagulopathies when documenting.
In Context
- "Preoperative evaluation revealed an underlying coagulopathy requiring hematology consultation." — Surgical planning
- "The patient's coagulopathy was attributed to chronic liver disease and vitamin K deficiency." — Clinical assessment