pressure gradient
Difference in blood pressure measured across a stenotic or diseased vessel segment.
Full Definition
A pressure gradient represents the difference in blood pressure measured proximal and distal to a stenotic or diseased vessel segment, indicating the hemodynamic significance of the lesion. Pressure gradients are measured during catheterization procedures using pressure-sensing guidewires or catheters positioned across the area of interest. Significant gradients suggest flow-limiting disease requiring intervention, while minimal gradients may indicate that stenosis is not hemodynamically significant. Gradient measurements help guide treatment decisions and assess procedural success following interventions.
Usage
Usage note: Always specify the anatomical location and numerical value when reporting gradients.
In Context
- "A pressure gradient of 50 mmHg across the renal artery stenosis confirmed hemodynamic significance." — Catheterization report
- "Post-angioplasty pressure gradient measurements showed successful reduction from 40 to 5 mmHg." — Procedure note