graft thrombosis
Blood clot formation within a surgical bypass graft, leading to graft failure and loss of blood flow.
Full Definition
Graft thrombosis represents complete occlusion of a surgical bypass graft due to intraluminal blood clot formation. This complication can occur in the immediate postoperative period (early thrombosis) or months to years later (late thrombosis). Early thrombosis is often related to technical factors, while late thrombosis typically results from progressive intimal hyperplasia, atherosclerotic progression, or inadequate antiplatelet therapy. Prompt recognition and treatment are essential for graft salvage.
Usage
Usage note: Distinguish between early (within 30 days) and late thrombosis; specify timing when relevant.
In Context
- "Early graft thrombosis occurred within 24 hours of the femoral-popliteal bypass procedure." — complication report
- "The patient presented with acute limb ischemia secondary to late graft thrombosis." — emergency department note