Intermediate
Technical
In the Industry Vocabulary Test
heparinization
Pronunciation: HEP-ah-rin-ih-ZAY-shun
The process of administering heparin to achieve therapeutic anticoagulation during vascular procedures.
Full Definition
Heparinization refers to the systematic administration of heparin, an anticoagulant medication, to prevent blood clotting during vascular surgical procedures. This process involves careful dosing calculations, typically based on patient weight, followed by monitoring of activated clotting time (ACT) to ensure adequate anticoagulation. Proper heparinization is crucial for preventing thrombosis during vessel manipulation, graft placement, and other vascular interventions while minimizing bleeding risks.
Usage
Usage note: Can refer to both systemic and local heparin administration techniques.
In Context
- "Systemic heparinization was achieved with 5000 units IV bolus followed by ACT monitoring." — operative report
- "Local heparinization of the graft was performed prior to anastomotic construction." — surgical documentation
Also known as
anticoagulation therapy
heparin administration
Contrasted with
heparin reversal
protamine administration
Don't confuse with
anticoagulation
heparin dosing