in-stent restenosis
Recurrent narrowing within a previously placed stent, typically due to neointimal hyperplasia or in-stent thrombosis.
Full Definition
In-stent restenosis refers to the development of recurrent stenosis within a previously implanted stent, most commonly caused by neointimal hyperplasia (cellular proliferation) or, less frequently, in-stent thrombosis. This complication represents a significant challenge in endovascular therapy and may require repeat intervention with balloon angioplasty, additional stenting, or surgical bypass. The time course and mechanism of in-stent restenosis differ from primary atherosclerotic disease, making accurate terminology essential for treatment planning. Editors should ensure that hyphenation is consistent and that the term is distinguished from primary stent thrombosis or external stent compression.
Usage
Usage note: Maintain consistent hyphenation. Distinguish from primary stent thrombosis.
In Context
- "The patient developed in-stent restenosis six months after carotid artery stenting." — Follow-up report
- "Treatment options for in-stent restenosis include balloon angioplasty or surgical bypass." — Treatment planning