buprenorphine

Full Definition

Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder and managing pain. As a partial agonist, it activates opioid receptors but produces a 'ceiling effect' that reduces the risk of overdose compared to full agonists. Common brand names include Suboxone (when combined with naloxone) and Subutex. The medication can be prescribed by qualified physicians in office-based settings, making it more accessible than methadone treatment.

Usage

Usage note: Often confused with naloxone or naltrexone; ensure accurate spelling and context when editing clinical documents.

In Context

• "The physician obtained a DEA waiver to prescribe buprenorphine in her primary care practice." — medical licensing document
• "Buprenorphine maintenance therapy showed superior retention rates compared to placebo in the clinical trial." — research publication