Vivitrol
Pronunciation: VIH-vih-trawl
Brand name for extended-release injectable naltrexone used in opioid and alcohol use disorder treatment.
Full Definition
Vivitrol is the brand name for extended-release naltrexone, an FDA-approved monthly injection used to treat both opioid use disorder and alcohol use disorder. As an opioid receptor antagonist, it blocks the euphoric effects of opioids and reduces alcohol cravings by modulating the brain's reward system. The injection provides consistent medication levels for 30 days, eliminating daily dosing compliance issues associated with oral naltrexone. Patients must be opioid-free for 7-14 days before starting Vivitrol to avoid precipitated withdrawal. The medication is most effective when combined with comprehensive addiction treatment including counseling and psychosocial support.
Usage
Usage note: Always capitalize as it is a proprietary brand name.
In Context
- "The patient received her first Vivitrol injection after completing a 10-day detoxification program." — Medical administration record
- "Vivitrol's monthly dosing schedule improved treatment retention compared to daily oral medications." — Clinical outcomes research