thelarche
Pronunciation: thee-LAR-kee
The onset of breast development, typically the first sign of puberty in girls.
Full Definition
Thelarche refers to the onset of breast development in girls, usually occurring between ages 8-13 and representing the first visible sign of pubertal development. Normal thelarche involves bilateral breast budding, though unilateral development may occur initially. Premature thelarche refers to isolated breast development before age 8 without other signs of puberty. Clinical assessment includes evaluation for underlying hormonal causes and monitoring for progression of other pubertal changes.
Usage
Usage note: Distinguish from 'premature thelarche' which occurs before age 8.
In Context
- "The patient experienced thelarche at age 9 with normal progression of pubertal development." — Pediatric growth assessment
- "Isolated thelarche without other pubertal signs prompted endocrine evaluation." — Specialist referral note