hypogonadotropic hypogonadism
Condition where low sex hormones result from inadequate pituitary or hypothalamic stimulation.
Full Definition
Hypogonadotropic hypogonadism occurs when the hypothalamus or pituitary fails to produce adequate gonadotropin-releasing hormone or gonadotropins, resulting in decreased sex hormone production and delayed or absent puberty. This condition can be congenital (such as Kallmann syndrome) or acquired through various causes including tumors, infections, or medications. Adolescent patients require comprehensive evaluation including olfactory testing, neuroimaging, and genetic analysis when indicated.
Usage
Usage note: Specify whether congenital or acquired; distinguish from primary gonadal failure.
In Context
- "MRI revealed a pituitary adenoma causing hypogonadotropic hypogonadism." — Endocrinology consultation note
- "The patient's hypogonadotropic hypogonadism required hormone replacement therapy." — Treatment planning documentation