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Professional Technical In the Industry Vocabulary Test

hypogonadotropic hypogonadism

Condition where low sex hormones result from inadequate pituitary or hypothalamic stimulation.

Full Definition

Hypogonadotropic hypogonadism occurs when the hypothalamus or pituitary fails to produce adequate gonadotropin-releasing hormone or gonadotropins, resulting in decreased sex hormone production and delayed or absent puberty. This condition can be congenital (such as Kallmann syndrome) or acquired through various causes including tumors, infections, or medications. Adolescent patients require comprehensive evaluation including olfactory testing, neuroimaging, and genetic analysis when indicated.

Usage

Usage note: Specify whether congenital or acquired; distinguish from primary gonadal failure.

In Context

  • "MRI revealed a pituitary adenoma causing hypogonadotropic hypogonadism." — Endocrinology consultation note
  • "The patient's hypogonadotropic hypogonadism required hormone replacement therapy." — Treatment planning documentation

Also known as

central hypogonadism secondary hypogonadism

Contrasted with

hypergonadotropic hypogonadism primary hypogonadism

Don't confuse with

hypergonadotropic hypogonadism constitutional delay

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