pulmonary hypertension
Elevated pressure in the pulmonary arteries, defined as mean pulmonary artery pressure ≥20 mmHg at rest.
Full Definition
Pulmonary hypertension (PH) is defined hemodynamically as a mean pulmonary artery pressure of 20 mmHg or greater at rest, as measured by right heart catheterization. The condition is classified into five groups based on underlying etiology: Group 1 (pulmonary arterial hypertension), Group 2 (left heart disease), Group 3 (lung disease/hypoxia), Group 4 (chronic thromboembolic), and Group 5 (unclear/multifactorial mechanisms). Symptoms include dyspnea, fatigue, chest pain, and syncope. Diagnosis requires comprehensive evaluation including echocardiography, right heart catheterization, and assessment for underlying causes. Treatment is group-specific and may include pulmonary vasodilators, diuretics, and addressing underlying conditions.
Usage
Usage note: Specify the WHO functional class and hemodynamic group when known.
In Context
- "Right heart catheterization confirmed the diagnosis of Group 2 pulmonary hypertension secondary to left heart failure." — Cardiology consultation
- "The patient's pulmonary hypertension was classified as Group 1 based on comprehensive hemodynamic assessment." — Pulmonary hypertension clinic note