extrapyramidal symptoms
Movement-related side effects of medications, typically antipsychotics, affecting the extrapyramidal motor system.
Full Definition
Extrapyramidal symptoms (EPS) are drug-induced movement disorders that result from blockade of dopamine receptors in the basal ganglia. These symptoms include acute dystonia, parkinsonism, akathisia, and tardive dyskinesia. EPS are most commonly associated with antipsychotic medications but can also occur with antiemetics and other dopamine-blocking drugs. The symptoms can be acute or chronic and may be reversible or irreversible depending on the specific type and duration of exposure.
Usage
Usage note: Commonly abbreviated as EPS in clinical documentation.
In Context
- "The patient developed extrapyramidal symptoms within days of starting haloperidol." — Adverse event report
- "EPS were managed with anticholinergic medication and dose reduction." — Treatment adjustment note