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fractional flow reserve
Hemodynamic measurement indicating the functional significance of coronary stenosis.
Full Definition
Fractional flow reserve (FFR) is a quantitative measure of the severity of coronary artery stenosis that determines whether a particular blockage is restricting blood flow enough to cause ischemia. The measurement compares maximum blood flow in a stenotic artery to theoretical maximum flow in the same artery if it were normal. FFR values below 0.80 are generally considered hemodynamically significant and may warrant intervention. This technique has revolutionized decision-making in coronary interventions by moving beyond anatomical assessment to functional evaluation.
Usage
Usage note: Lowercase when spelled out; FFR when abbreviated.
In Context
- "The fractional flow reserve measurement of 0.75 indicated hemodynamically significant stenosis requiring intervention." — Catheterization lab report
- "FFR-guided PCI has been shown to improve clinical outcomes compared to angiography-guided procedures." — Clinical research paper
Also known as
FFR
Don't confuse with
coronary flow reserve
myocardial flow reserve