Retinoid
Pronunciation: RET-ih-noyd
A class of vitamin A derivatives used topically or systemically to promote cell turnover, stimulate collagen, and reduce pigmentation, frequently referenced in aesthetic dermatology prescribing and pre-treatment preparation protocols.
Full Definition
Retinoids are a broad class of vitamin A compounds that include retinol (over-the-counter), retinaldehyde, tretinoin (prescription), and isotretinoin (systemic). In aesthetic dermatology, topical retinoids are prescribed as part of skin preparation regimens before procedures such as chemical peels and laser resurfacing, as well as for ongoing maintenance of treatment outcomes. They act by binding nuclear retinoic acid receptors to regulate gene expression, increasing epidermal turnover and stimulating dermal collagen synthesis. Editors encounter the term in prescribing information, consent forms, protocol documents, and marketing content. A frequent editorial error is using 'retinol' and 'retinoid' interchangeably; retinol is a specific retinoid of comparatively lower potency.
Usage
Usage note: 'Retinoid' is the class term; 'retinol' and 'tretinoin' are specific members of the class. Editors should not use these interchangeably without clinical justification.
In Context
- "Patients were advised to discontinue retinoid therapy two weeks prior to the ablative laser procedure." — Pre-procedure protocol
- "The consent form listed retinoid sensitivity as a contraindication to the medium-depth peel." — Informed consent document