verapamil-sensitive VT
Pronunciation: ver-AP-ah-mil SEN-si-tiv VT
A specific type of ventricular tachycardia that responds to verapamil therapy. Typically originates from the right ventricular outflow tract.
Full Definition
Verapamil-sensitive VT refers to a specific subset of ventricular tachycardia that is terminated or suppressed by verapamil, a calcium channel blocker. This arrhythmia typically arises from the right ventricular outflow tract (RVOT) and has characteristic electrocardiographic features including a left bundle branch block morphology with inferior axis. The mechanism involves cyclic adenosine monophosphate (cAMP)-mediated triggered activity that is calcium-dependent, making it uniquely responsive to calcium channel blockade. This form of VT is generally considered benign compared to other ventricular arrhythmias and often occurs in patients with structurally normal hearts.
Usage
Usage note: Use 'verapamil-sensitive' as a compound adjective; hyphenate when modifying VT.
In Context
- "The narrow QRS morphology and response to adenosine suggested verapamil-sensitive VT rather than SVT with aberrancy." — Emergency department report
- "Verapamil-sensitive VT typically presents with exercise-induced palpitations in young, otherwise healthy patients." — Electrophysiology study report