Polycystic Ovary Syndrome
Also written as: PCOS — Polycystic Ovary Syndrome
A common endocrine disorder characterized by irregular ovulation, hyperandrogenism, and polycystic ovarian morphology.
Full Definition
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility, affecting 5-10% of reproductive-age women. The condition is diagnosed based on the Rotterdam criteria, which require two of three features: oligo-ovulation or anovulation, clinical or biochemical hyperandrogenism, and polycystic ovaries on ultrasound. PCOS patients often present with irregular menstrual cycles, hirsutism, acne, and insulin resistance. In fertility treatment, PCOS patients may require specialized protocols due to increased risk of ovarian hyperstimulation syndrome and multiple pregnancies. Treatment approaches include lifestyle modifications, ovulation induction with clomiphene or letrozole, and assisted reproductive technologies when first-line treatments fail.
Usage
Usage note: Always specify diagnostic criteria used when documenting PCOS diagnosis.
In Context
- "The patient's history of polycystic ovary syndrome required modified stimulation protocols." — Treatment planning note
- "Polycystic ovary syndrome diagnosis was confirmed using Rotterdam criteria." — Clinical assessment