Preimplantation Genetic Testing
Also written as: PGT — Preimplantation Genetic Testing
Genetic screening of embryos before transfer to identify chromosomal or genetic abnormalities.
Full Definition
Preimplantation genetic testing encompasses various techniques used to analyze embryos for genetic and chromosomal abnormalities before transfer during an IVF cycle. PGT includes testing for aneuploidy (PGT-A), monogenic diseases (PGT-M), and structural chromosomal rearrangements (PGT-SR). The procedure involves removing a few cells from the embryo at the blastocyst stage and analyzing them using advanced genetic technologies. PGT helps reduce the risk of genetic diseases and pregnancy loss while improving the chances of a healthy pregnancy.
Usage
Usage note: Use PGT as the umbrella term; specify PGT-A, PGT-M, or PGT-SR for precise testing types.
In Context
- "PGT-A revealed three euploid blastocysts suitable for transfer." — genetic counselor report
- "The couple elected for preimplantation genetic testing due to advanced maternal age." — informed consent form