Vitrification
An ultra-rapid freezing technique used to preserve eggs, sperm, and embryos without ice crystal formation.
Full Definition
Vitrification is an advanced cryopreservation method that rapidly cools biological samples to extremely low temperatures (-196°C) at rates exceeding 15,000°C per minute, creating a glass-like state without ice crystal formation. This technique has revolutionized fertility preservation by dramatically improving survival rates of frozen eggs, sperm, and embryos compared to traditional slow-freeze methods. Vitrification requires specialized equipment, cryoprotectants, and precise timing to achieve optimal results. The process is reversible through rapid warming, allowing preserved gametes and embryos to maintain their viability for future use in assisted reproductive procedures.
Usage
Usage note: Distinguish from conventional slow-freeze methods when discussing cryopreservation techniques.
In Context
- "Egg vitrification was performed for fertility preservation before cancer treatment." — Oncofertility consultation
- "The laboratory achieved excellent post-thaw survival rates using vitrification protocols." — Quality metrics report