Intermediate
Technical
IVT
contralateral breast cancer
Development of a new primary cancer in the opposite breast from the original tumor.
Full Definition
Contralateral breast cancer refers to the occurrence of cancer in the breast opposite to the side of the original primary tumor. This can be synchronous (detected within 6 months of the initial diagnosis) or metachronous (detected more than 6 months after initial diagnosis). The risk varies based on factors including age at first diagnosis, family history, genetic mutations (particularly BRCA1/2), and histological features. Contralateral cancers represent new primary tumors rather than metastatic disease and require independent staging and treatment planning.
Usage
Usage note: Specify whether synchronous or metachronous when relevant to treatment decisions.
In Context
- "Surveillance imaging detected contralateral breast cancer five years after initial treatment." — follow-up report
- "BRCA mutation carriers have elevated risk for contralateral breast cancer development." — genetic counseling documentation
Also known as
opposite breast cancer
Contrasted with
ipsilateral breast cancer
Don't confuse with
bilateral breast cancer
metastatic disease