microcalcification cluster
A group of tiny calcium deposits in breast tissue visible on mammography, potentially indicating ductal carcinoma in situ or invasive cancer.
Full Definition
A microcalcification cluster refers to a collection of small calcium deposits (typically ≥5 microcalcifications within 1 cm²) detected on mammographic imaging. These clusters are significant because they may represent the only mammographic sign of early breast cancer, particularly ductal carcinoma in situ. The morphology and distribution of microcalcifications within the cluster are analyzed according to BI-RADS criteria to determine suspicion level. Suspicious characteristics include linear, branching, or pleomorphic morphology and segmental or linear distribution, which often warrant tissue sampling for histologic diagnosis.
Usage
Usage note: Always describe morphology and distribution characteristics when reporting suspicious clusters.
In Context
- "A new microcalcification cluster measuring 8 mm is identified in the upper outer quadrant, BI-RADS 4B." — Mammography report
- "Stereotactic biopsy of the microcalcification cluster yielded high-grade ductal carcinoma in situ." — Pathology correlation note