multifocal breast cancer

Full Definition

Multifocal breast cancer refers to the presence of two or more separate tumor foci within the same breast quadrant, with each focus separated by normal breast tissue. This is distinguished from multicentric disease, where tumors occur in different quadrants. Multifocal disease may arise from a single primary tumor with local spread or represent multiple independent primary tumors. The condition affects surgical planning, as breast-conserving surgery may still be feasible depending on the size and distribution of foci, though wider excision or mastectomy might be necessary.

Usage

Usage note: Distinguish clearly from multicentric disease in documentation.

In Context

• "MRI revealed multifocal breast cancer with three distinct enhancing lesions." — imaging report
• "Multifocal disease complicated the surgical approach but breast conservation remained feasible." — surgical planning note