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IVT
zone of coagulation
The central area of a burn wound where tissue death is immediate and irreversible.
Full Definition
The zone of coagulation represents the central core of a burn injury where thermal damage is most severe and tissue necrosis is immediate and irreversible. This zone is characterized by coagulated proteins, thrombosed vessels, and cell death. Surrounding this central zone are the zone of stasis (potentially salvageable tissue) and zone of hyperemia (viable tissue with increased blood flow). Understanding these zones is crucial for burn assessment, treatment planning, and predicting healing outcomes.
Usage
Usage note: Always considered in context of the three-zone model of burn injury pathophysiology.
In Context
- "The zone of coagulation required immediate surgical excision and grafting." — Burn assessment report
- "Tissue within the zone of coagulation shows no potential for spontaneous healing." — Pathophysiology documentation
Also known as
zone of necrosis
Contrasted with
zone of hyperemia
Don't confuse with
zone of stasis
zone of hyperemia