cerium nitrate
Pronunciation: SEER-ee-um NYE-trate
Topical antimicrobial agent combined with silver sulfadiazine, particularly effective against resistant organisms in burn wounds.
Full Definition
Cerium nitrate is a topical antimicrobial agent typically combined with silver sulfadiazine for treatment of burn wounds. Cerium has unique antimicrobial properties and forms a protective leather-like eschar that helps prevent bacterial penetration. This combination is particularly effective against antibiotic-resistant organisms and has been shown to reduce mortality in extensive burns. The cerium-silver sulfadiazine combination creates an immediate antimicrobial barrier while promoting controlled eschar formation.
Usage
Usage note: Often abbreviated as Ce-SSD when combined with silver sulfadiazine; note the characteristic eschar formation.
In Context
- "Cerium nitrate cream was applied to combat the multidrug-resistant Pseudomonas colonization." — Treatment modification note
- "The leather-like eschar formation following cerium nitrate application provided excellent wound protection." — Progress documentation