molecular tumor board
Also written as: MTB — molecular tumor board
A multidisciplinary team that reviews complex cases to recommend treatment based on tumor genomic profiling.
Full Definition
A molecular tumor board (MTB) is a specialized multidisciplinary team that meets regularly to review complex cancer cases and provide treatment recommendations based on comprehensive genomic profiling and molecular characteristics of tumors. The team typically includes medical oncologists, pathologists, molecular biologists, pharmacists, and genetic counselors who collectively interpret genomic sequencing results, identify actionable mutations, and recommend targeted therapies or clinical trials. MTBs are particularly valuable for patients with rare cancers, treatment-refractory disease, or tumors harboring unusual molecular alterations. These boards bridge the gap between genomic discovery and clinical application, ensuring that patients receive the most appropriate precision medicine approaches.
Usage
Usage note: Can be abbreviated as MTB. Distinguish from traditional tumor boards that focus on staging and standard treatment.
In Context
- "The case was presented to the molecular tumor board for treatment recommendations." — Referral documentation
- "MTB review identified a targetable NTRK fusion in the patient's sarcoma." — Molecular tumor board report