Cancer Biology Glossary
100 terms total — 5 showing — Last updated 15 Sep 2026
Adoptive Cell Therapy ACT
Treatment approach involving the extraction, modification, and reinfusion of a patient's immune cells to enhance anti-tumor activity.
chromosomal instability
Increased rate of chromosome structure or number alterations during cell division.
dose-limiting toxicity
The adverse effects that prevent further dose escalation in cancer treatment, typically defined in clinical trials to es...
microsatellite instability
A molecular phenotype caused by defective DNA mismatch repair, resulting in hypermutation and immunotherapy sensitivity.
microsatellite stable
A tumor classification indicating normal DNA mismatch repair function and low immunotherapy responsiveness.
Microsatellite-High
Tumor phenotype characterized by widespread instability in microsatellite DNA sequences due to mismatch repair deficienc...