LSIL
Pronunciation: L-S-I-L
Also written as: LSIL — Low-grade Squamous Intraepithelial Lesion
Cytological finding indicating mild cervical cellular changes typically caused by HPV infection with low cancer risk.
Full Definition
Low-grade Squamous Intraepithelial Lesion represents mild cellular abnormalities in cervical cytology specimens, corresponding histologically to CIN 1. LSIL changes often reflect transient HPV infection and frequently resolve spontaneously, particularly in younger women. Management typically involves observation or follow-up testing rather than immediate intervention, as progression to high-grade lesions or cancer is uncommon.
Usage
Usage note: Pronounced as individual letters (L-S-I-L), not as a word; spell out on first use in patient communications.
In Context
- "The cytology report showed LSIL with concurrent positive HPV testing in a 28-year-old patient." — Laboratory report
- "Follow-up guidelines for LSIL vary based on patient age and HPV co-testing results." — Clinical protocol document