del Nido cardioplegia
Pronunciation: del NEE-do
A single-dose, high-volume cardioplegic solution that provides extended myocardial protection during cardiac surgery.
Full Definition
Del Nido cardioplegia is a myocardial protection strategy developed by Dr. Pedro del Nido that uses a single, large-volume dose of cardioplegic solution to arrest and protect the heart during surgery. This technique differs from traditional multi-dose cardioplegia protocols by providing 60-90 minutes of protection with one administration. The solution contains lidocaine for membrane stabilization, mannitol for cellular protection, and is diluted with the patient's blood to maintain oncotic pressure. Del Nido cardioplegia has gained popularity because it reduces cross-clamp interruptions for re-dosing, potentially improving surgical efficiency while maintaining excellent myocardial protection. The technique is particularly useful for complex procedures requiring extended cross-clamp times.
Usage
Usage note: Lowercase 'del' and capitalize 'Nido' as per the inventor's name; do not use quotation marks.
In Context
- "Del Nido cardioplegia was administered through the aortic root, providing 75 minutes of cardiac arrest." — operative report
- "The institution adopted del Nido cardioplegia protocols for all pediatric cardiac cases." — policy document