Anisotropic Conduction
Pronunciation: /ˌænɪsoʊˈtrɒpɪk/
Directional dependence of electrical conduction velocity in cardiac tissue due to fiber orientation and gap junction distribution.
Full Definition
Anisotropic conduction describes the phenomenon where electrical impulse propagation velocity varies significantly depending on direction relative to myocardial fiber orientation. Conduction is typically faster parallel to fiber direction (longitudinal) and slower perpendicular to fibers (transverse). This property is fundamental to understanding reentrant arrhythmia mechanisms, particularly in areas of scar tissue where anisotropy is enhanced. Ablation strategies often target areas where anisotropic conduction creates slow conduction channels that sustain ventricular tachycardia.
Usage
Usage note: Often confused with general tissue heterogeneity. Specifically refers to directional conduction properties.
In Context
- "The scar border zone exhibited marked anisotropic conduction with preferential propagation along surviving fiber bundles." — Electrophysiology study report
- "Anisotropic conduction properties were altered in the infarct region, creating the substrate for ventricular tachycardia." — Research manuscript