diastolic dysfunction
Impaired relaxation and filling of the left ventricle during diastole, often assessed by echocardiographic parameters.
Full Definition
Diastolic dysfunction refers to abnormal left ventricular relaxation, distensibility, or filling that can occur with normal or reduced ejection fraction. This condition is characterized by increased left ventricular filling pressures and is commonly associated with heart failure with preserved ejection fraction (HFpEF). Echocardiographic assessment includes evaluation of mitral inflow patterns, tissue Doppler imaging, and left atrial size. Diastolic dysfunction is graded as mild (grade I), moderate (grade II), or severe (grade III) based on established criteria. The condition is particularly prevalent in elderly patients and those with hypertension, diabetes, and obesity.
Usage
Usage note: Grade using established criteria (I-III). Distinguish from systolic dysfunction and diastolic murmurs.
In Context
- "Moderate diastolic dysfunction was noted with elevated E/e' ratio." — Echocardiography report
- "The patient has heart failure with preserved ejection fraction and severe diastolic dysfunction." — Cardiology consultation