drug-eluting stent
Also written as: DES — Drug-Eluting Stent
A coronary stent coated with medication to prevent restenosis after implantation.
Full Definition
A drug-eluting stent (DES) is a small mesh tube placed in coronary arteries during PCI that slowly releases medication to prevent the re-narrowing of the vessel. These stents are coated with antiproliferative drugs such as sirolimus, paclitaxel, or everolimus that inhibit smooth muscle cell proliferation and reduce the risk of in-stent restenosis. DES have largely replaced bare-metal stents in clinical practice due to their superior long-term outcomes. However, they require prolonged dual antiplatelet therapy to prevent stent thrombosis.
Usage
Usage note: Hyphenate when used as compound modifier; capitalize acronym DES.
In Context
- "The second-generation drug-eluting stent showed excellent patency rates at one-year follow-up." — Clinical trial report
- "Drug-eluting stents require extended dual antiplatelet therapy to minimize thrombotic complications." — Treatment guideline