dual antiplatelet therapy
Also written as: DAPT — Dual Antiplatelet Therapy
The combination of aspirin and a P2Y12 inhibitor to prevent thrombotic events after coronary stenting.
Full Definition
Dual antiplatelet therapy (DAPT) consists of aspirin plus a P2Y12 receptor inhibitor (such as clopidogrel, prasugrel, or ticagrelor) used to prevent stent thrombosis and other atherothrombotic events following PCI. The standard duration varies depending on clinical presentation, stent type, and bleeding risk, typically ranging from one month to over 12 months. DAPT is essential after coronary stenting but increases bleeding risk, requiring careful balance between thrombotic and hemorrhagic complications. Guidelines provide specific recommendations for DAPT duration based on patient and procedural factors.
Usage
Usage note: DAPT is the standard acronym; avoid DAT which may be confused with other therapies.
In Context
- "The patient was prescribed dual antiplatelet therapy for 12 months following drug-eluting stent implantation." — Discharge summary
- "Dual antiplatelet therapy duration should be individualized based on ischemic and bleeding risk assessment." — Clinical guideline