fractional flow reserve
Also written as: FFR — Fractional Flow Reserve
A physiological measurement used to assess the functional significance of coronary stenosis during catheterization.
Full Definition
Fractional flow reserve (FFR) is an invasive diagnostic technique that measures the pressure gradient across a coronary stenosis during maximal hyperemia. The measurement provides a functional assessment of whether a particular coronary lesion is causing ischemia and would benefit from revascularization. An FFR value of 0.80 or less is considered hemodynamically significant and typically indicates the need for intervention. FFR-guided PCI has been shown to improve clinical outcomes compared to angiography-guided procedures alone.
Usage
Usage note: Do not capitalize when spelled out unless at beginning of sentence; always capitalize acronym FFR.
In Context
- "Fractional flow reserve measurement revealed hemodynamically significant stenosis in the left anterior descending artery." — Catheterization report
- "The use of fractional flow reserve guidance reduced unnecessary stent implantations by 30%." — Clinical study