thrombolytic therapy
Treatment using clot-dissolving medications for acute cardiovascular conditions, with strict timing and contraindication documentation requirements.
Full Definition
Medical treatment involving the administration of medications that dissolve blood clots by activating the fibrinolytic system, primarily used in acute myocardial infarction and pulmonary embolism management. Common thrombolytic agents include alteplase (tPA), reteplase, and streptokinase. Medical editors encounter thrombolytic protocols in emergency medicine documentation, with detailed time-sensitive criteria for administration including door-to-needle times and absolute contraindications. The documentation must include pre-treatment assessment for bleeding risk, informed consent considerations, and post-treatment monitoring for both therapeutic response and hemorrhagic complications. This therapy is often contrasted with primary PCI in STEMI management protocols.
Usage
Usage note: Include specific agent name, dosing, and timing; document contraindications thoroughly.
In Context
- "Thrombolytic therapy was administered within the recommended time window for STEMI." — Emergency medicine procedure note
- "The patient was excluded from thrombolytic therapy due to recent surgery." — Acute care contraindication documentation