glycemic excursion
Significant deviations from target glucose range, particularly post-meal glucose spikes measured by continuous monitoring.
Full Definition
Glycemic excursions refer to significant fluctuations in blood glucose levels, particularly rapid rises above target ranges following meals or other triggers. These excursions are increasingly recognized as important contributors to cardiovascular risk independent of average glucose control (HbA1c). Continuous glucose monitoring has revealed that glycemic excursions, including both hyperglycemic spikes and hypoglycemic episodes, may promote oxidative stress, inflammation, and endothelial dysfunction. Modern diabetes management emphasizes reducing both the magnitude and frequency of glycemic excursions.
Usage
Usage note: Often quantified using metrics like mean amplitude of glycemic excursions (MAGE) or coefficient of variation.
In Context
- "Continuous glucose monitoring revealed frequent glycemic excursions despite acceptable HbA1c levels." — Diabetes management report
- "The new insulin regimen successfully reduced both average glucose and glycemic excursions." — Treatment response assessment