MOLLI

Full Definition

Modified Look-Locker inversion recovery is the most widely used pulse sequence for cardiac T1 mapping, providing rapid quantification of myocardial T1 relaxation times. MOLLI acquires multiple images at different inversion times following a single inversion pulse, allowing T1 map generation in a single breath-hold. The technique enables detection of diffuse myocardial fibrosis and infiltrative diseases that may not be visible on conventional late gadolinium enhancement imaging.

Usage

Usage note: Capitalize all letters when used as abbreviation.

In Context

• "Native MOLLI T1 values were elevated throughout the myocardium, suggesting infiltrative cardiomyopathy." — T1 mapping analysis report
• "Post-contrast MOLLI acquisition was performed 15 minutes after gadolinium administration." — Cardiac MRI protocol timing