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Advanced Technical IVT

contrast nephropathy

Acute kidney injury following intravascular contrast media administration during cardiac procedures.

Full Definition

Contrast-induced nephropathy (CIN) is an acute deterioration in renal function occurring within 48-72 hours following intravascular administration of iodinated contrast media during cardiac catheterization or CT angiography. The condition is defined as an absolute increase in serum creatinine ≥0.5 mg/dL or relative increase ≥25% from baseline. Risk factors include pre-existing chronic kidney disease, diabetes mellitus, advanced age, dehydration, and high contrast volume. Prevention strategies include adequate hydration, use of iso-osmolar or low-osmolar contrast agents, minimizing contrast volume, and consideration of alternative imaging modalities in high-risk patients. Most cases are reversible, but severe CIN may require dialysis.

Usage

Usage note: Distinguish from other causes of post-procedural acute kidney injury

In Context

  • "Prophylactic hydration was initiated to minimize contrast nephropathy risk." — Pre-procedure planning
  • "Post-procedural creatinine elevation suggested possible contrast nephropathy." — Follow-up assessment

Also known as

CIN contrast-induced nephropathy contrast-associated acute kidney injury

Don't confuse with

acute kidney injury nephrotoxicity

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